A pandemic warning?
Identifieur interne : 001B27 ( Main/Exploration ); précédent : 001B26; suivant : 001B28A pandemic warning?
Auteurs : J. C. De Jong [Pays-Bas] ; E. C. J. Claas [Pays-Bas] ; A. D. M. E. Osterhaus [Pays-Bas] ; R. G. Webster ; W. L. LimSource :
- Nature [ 0028-0836 ] ; 1997.
Abstract
Introduction of new influenza type-A viruses, carrying different combinations of the viral envelope glycoproteins haemagglutinin (H) and neuraminidase (N), have led to three major pandemics of influenza in humans this century. Phylogenetic evidence suggests that these viruses have originated from avian influenza A viruses, either unchanged or after reassortment with humaninfluenza A viruses. In aquatic birds, all of the known H and N antigenic varieties (15 varieties carry H, nine carry N envelope glycoproteins) apparently circulate in a genetically conserved fashion. Viruses carrying the H1N1, H2N2 and H3N2 combinations were responsible for the Spanish flu of 1918, the Asian flu in 1957 and Hong Kong flu in 1968, respectively
Url:
DOI: 10.1038/39218
PubMed: 9335492
PubMed Central: 7095477
Affiliations:
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C." last="De Jong">J. C. De Jong</name><affiliation wicri:level="1"><nlm:aff id="Aff1">National Influenza Centre of The Netherlands, Erasmus University Rotterdam and National Institute of Public Health and the Environment, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>National Influenza Centre of The Netherlands, Erasmus University Rotterdam and National Institute of Public Health and the Environment, Dr. Molewaterplein 50, 3015 GE Rotterdam</wicri:regionArea><wicri:noRegion>3015 GE Rotterdam</wicri:noRegion></affiliation></author><author><name sortKey="Claas, E C J" sort="Claas, E C J" uniqKey="Claas E" first="E. C. J." last="Claas">E. C. J. Claas</name><affiliation wicri:level="1"><nlm:aff id="Aff1">National Influenza Centre of The Netherlands, Erasmus University Rotterdam and National Institute of Public Health and the Environment, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>National Influenza Centre of The Netherlands, Erasmus University Rotterdam and National Institute of Public Health and the Environment, Dr. Molewaterplein 50, 3015 GE Rotterdam</wicri:regionArea><wicri:noRegion>3015 GE Rotterdam</wicri:noRegion></affiliation></author><author><name sortKey="Osterhaus, A D M E" sort="Osterhaus, A D M E" uniqKey="Osterhaus A" first="A. D. M. E." last="Osterhaus">A. D. M. E. Osterhaus</name><affiliation wicri:level="1"><nlm:aff id="Aff1">National Influenza Centre of The Netherlands, Erasmus University Rotterdam and National Institute of Public Health and the Environment, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>National Influenza Centre of The Netherlands, Erasmus University Rotterdam and National Institute of Public Health and the Environment, Dr. Molewaterplein 50, 3015 GE Rotterdam</wicri:regionArea><wicri:noRegion>3015 GE Rotterdam</wicri:noRegion></affiliation></author><author><name sortKey="Webster, R G" sort="Webster, R G" uniqKey="Webster R" first="R. G." last="Webster">R. G. Webster</name><affiliation><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="GRID">grid.240871.8</institution-id><institution-id institution-id-type="ISNI">0000 0001 0224 711X</institution-id><institution>Department of Virology and Molecular Biology,</institution><institution>Saint Jude Childrens Research Hospital,</institution></institution-wrap>332 North Lauderdale Street, Memphis, 38105-2794 Tennessee USA</nlm:aff><wicri:noCountry code="subfield">38105-2794 Tennessee USA</wicri:noCountry></affiliation></author><author><name sortKey="Lim, W L" sort="Lim, W L" uniqKey="Lim W" first="W. L." last="Lim">W. L. Lim</name><affiliation><nlm:aff id="Aff3">Department of Health, Government Virus Unit, Queen Mary Hospital, The Hong Kong Special Administrative Region, ,</nlm:aff><wicri:noCountry code="subfield">The Hong Kong Special Administrative Region</wicri:noCountry></affiliation></author></analytic><series><title level="j">Nature</title><idno type="ISSN">0028-0836</idno><idno type="eISSN">1476-4687</idno><imprint><date when="1997">1997</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">Introduction of new influenza type-A viruses, carrying different combinations of the viral envelope glycoproteins haemagglutinin (H) and neuraminidase (N), have led to three major pandemics of influenza in humans this century. Phylogenetic evidence suggests that these viruses have originated from avian influenza A viruses, either unchanged or after reassortment with humaninfluenza A viruses. In aquatic birds, all of the known H and N antigenic varieties (15 varieties carry H, nine carry N envelope glycoproteins) apparently circulate in a genetically conserved fashion. Viruses carrying the H1N1, H2N2 and H3N2 combinations were responsible for the Spanish flu of 1918, the Asian flu in 1957 and Hong Kong flu in 1968, respectively<sup><xref ref-type="bibr" rid="CR1">1</xref></sup>. An influenza A virus of the H5N1 subtype has now been identified in a human patient, raising discussions about its potential to spark a new human influenza pandemic.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Pays-Bas</li></country></list><tree><noCountry><name sortKey="Lim, W L" sort="Lim, W L" uniqKey="Lim W" first="W. L." last="Lim">W. L. Lim</name><name sortKey="Webster, R G" sort="Webster, R G" uniqKey="Webster R" first="R. G." last="Webster">R. G. Webster</name></noCountry><country name="Pays-Bas"><noRegion><name sortKey="De Jong, J C" sort="De Jong, J C" uniqKey="De Jong J" first="J. C." last="De Jong">J. C. De Jong</name></noRegion><name sortKey="Claas, E C J" sort="Claas, E C J" uniqKey="Claas E" first="E. C. J." last="Claas">E. C. J. Claas</name><name sortKey="Osterhaus, A D M E" sort="Osterhaus, A D M E" uniqKey="Osterhaus A" first="A. D. M. E." last="Osterhaus">A. D. M. E. Osterhaus</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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